Listed on NASDAQ (NXTM) in October 2005

NxStage Medical, Inc. was founded in 1998 to develop and market novel technologies for the treatment of kidney failure. The NxStage System One is a breakthrough design that delivers hemodialysis, hemofiltration, and/or ultrafiltration to patients with renal failure or fluid overload. The system is compact and portable; it requires only a standard electrical outlet and no water processing. Its user-friendly interface and drop-in, disposable cartridge are designed for ease-of-use and streamlined training. The System One is FDA cleared, and is available commercially.